MCPDT

PURPOSE: R package that performs linkage disequilibrium test and parent-of-origin tests in the presence of association using pedigree data. Families with missing genotype data are allowed; Monte Carlo samples of the missing genotypes conditional on the observed data will be used.

Compiled R package file for Windows (in a zipped file)

Source R package file for Linux and Mac (in a zipped, tar file)

Sample pedigree file

Instructions

References:

Jie Ding, Shili Lin, Yang Liu (2006). Monte Carlo Pedigree Disequilibrium Test for Markers on X Chromosome. American Journal of Human Genetics, 79, 567-573. [abstract] [full text]

Zhou, J., Ding, J., Fung, W., Lin, S. (2009) Detection of Parent-of-Origin Effects Using General Pedigree Data. Genetic Epidemiology, in press. [full text]