Gamma-Normal-Gamma Mixture Model
NOTE: The GNG model is now part of the ensemble
in the DIME package, which we recommend.
PURPOSE:
Differential analysis for sequencing data as well as gene expression and methylation
microarray data.
GNG R package for linux/mac (in a zipped, tar file)
Instructions
References:
Khalili A, Potter D., Yan P, Li L, Gray J, Huang T.H.-M., S. Lin (2007) Gamma-No
rmal-Gamma Mixture Model for Detecting Differentially Methylated Loci in Three
Breast Cancer Cell Lines. Cancer Informatics 2:43-54.
Khalili A, Huang T.H.-M., Lin S (2008) A robust unified approach to analyzing methylation and gene
expression data. Computational Statistics and Data Analysis.
Available online at http://doi:10.1016/j.csda.2008.07.010.