CSI
PURPOSE: Uses affected sib pairs and IBD sharing probabilities at the
location of the putative trait loci to construct a confidence region
for its location. The two main programs are CSI and BOOTS.
Software (in a zipped, tar file)
Instructions for the CSI
References:
- Lin, S., Rogers, J.A., and Hsu, J.C. (2001)
A confidence set approach for finding tightly linked genomic regions.
American Journal of Human Genetics, 68, 1219-1228.
- Papachristou, C., Lin, S. (2006)
Microsatellites Versus Single-Nucleotide Polymorphisms in
Confidence Interval Estimation of Disease Loci.
Genetic Epidemiology, 30, 3-17.
- Papachristou, C., Lin, S. (2006)
A Two-Step Procedure for Constructing Confidence Intervals
of Trait Loci with Application to a
Rheumatoid Arthritis Dataset.
Genetic Epidemiology, 30, 18-29.
- Papachristou, C., Lin, S. (2006) A Comparison of Methods for Intermediate Fine Mapping.
Genetic Epidemiology, 30, 677-689.