HyDe (Hybrid Detection)

Version 1.0
Laura Kubatko and Julia Chifman
Departments of Statistics and Evolution, Ecology, and Organismal Biology
The Ohio State University


Copyright 2015, 2016 by Laura Kubatko and Julia Chifman. This software is provided "as is" without warranty of any kind. In no event shall the author be held responsible for any damage resulting from the use of this software. The program package, including source codes, executables, and documentation, is distributed free of charge. This software is covered under the Gnu GPL (General Public License).

The method is described in the following paper:

Kubatko, L. and J. Chifman. 2015. An invariants-based method for efficient identification of hybrid speciation from large-scale genomic data, submitted.
Available on bioRXiv.


About the Program

HyDe (Hybridization Detection) is a C program that computes the Hils statistic for all sets of three taxa and an outgroup in a given Phylip-formatted input file. The output of the program is a list of test statistics and p-values for the Hils test that can be used to assess statistically significant evidence for hybridization. Instructions for running the program are here.



Download (Updated Version Feb 1 2017):


Compiling the program (Linux/Unix/Mac OSX):
  1. Unzip the program files and cd into the directory in which the files are stored.
  2. Type make at the prompt.
  3. To run the program, type ./HyDe at the prompt.


Acknowledgements

Development of HyDe was partially supported by the National Science Foundation under Grant DEB-1106706. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.



Contact Info

Questions or comments concerning the program can be e-mailed to Laura Kubatko at kubatko.2@osu.edu.




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