ESS Quick Reference

From now on, split your window in two (Control x 2 or Control x 3).

In one of the windows, start S by hitting the escape key followed by x and when prompted with a question, answering S.

Now in the other half of the window, you open up a file, say file.s

To send a line to S, you put your cursor anywhere on the line and type C-c C-j [this means control c control j] (or you can hit the add key on the right keypad)

To send a region to S, you highlight the desired region and type C-c C-r (or you can hit the add key on the right keypad while the control key is pressed)

To send the whole buffer (i.e. the file, whether or not it is saved) you type C-c C-b (or you hit the add key on the keypad, while holding down both the control and alt keys)

If you want some color in your emacs session, then add to your .emacs.more file the following line:
(global-font-lock-mode t)